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TNT™ is a non-drug approach using low dosages of the safest, most efficacious natural ingredients, enhanced by a unique, proprietary delivery system blend. The formulas are designed by Sanesco to elicit specific metabolic responses for the restoration of function in the HPA-T axis.*

The Targeted Nutritional Therapy TNT™ formulas are designed to achieve excellent clinical outcomes with minimal side effects. Sanesco’s TNT™ line utilizes fewer products, meaning fewer capsules per day, which saves money and promotes patient compliance.

Targeted Nutritional Therapy Formulation

Ingredient Sourcing

Through our network of raw material partners and warehousing facilities strategically located from across the world, we are able to formulate with only the finest raw materials of the highest quality available – which correlates to effective formulations.
Targeted Nutritional Therapy Formulation

Manufacturing

Sanesco Health partners with a cGMP leader in contract manufacturing who continually strives to maintain an unwavering reputation for the delivery of exceptional formulas, where quality and dependability are of paramount importance.

10+ Years of Clinical Outcomes and Patient Satisfaction

INHIBITORY FORMULAS

Our inhibitory support products focus on increasing the neurotransmission and function of the inhibitory neurotransmitters, Serotonin and GABA, by providing essential precursors and cofactors for  their respective biochemical pathways.

Tranquilent™ | 30 tablets

Low doses of 5-HTP and Suntheanine® in this chewable tablet are absorbed quickly when symptoms of anxiety or OCD require immediate relief*

Prolent™ | 60 capsules

Helps rebuild Serotonin and supports inhibitory neurotransmission, including support for GABA-A receptors, Glycine, and cofactor Vitamin B6 as P5P*

Lentra™ | 30/60 capsules

Use when an assessment shows GABA is below reference range or is insufficient to control excitatory neurotransmitter levels*

Featured Ingredients

L-theanine

B12 Vitamin

Bioperine®

5-HTP from Griffonia simplicifolia

Magnesium (as Magnesium Taurate)

Magnesium (Mg) is a chemical element and the fourth most prevalent mineral in the body. Approximately half of the human body’s total Mg is found in bone, while the other half is predominantly found in body tissue and organ cells. Comprised of two taurine molecules molecularly-bound to one positively charged magnesium molecule, this salt form is extremely water soluble, so upon entering the body, it can easily be broken down.

Lactium®

In an attempt to isolate the reason for the calming effect of milk, Lactium® was discovered. Lactium® is a hypoallergenic 10-amino-acid peptide that comes from casein, the family of proteins found in dairy products. Through multiple studies it has displayed calming, but not sedative, effects.

NSB™

Sanesco Health’s NSB™ is a proprietary nutrient absorption enhancement system containing compounds which are scientifically valid and evidence-based to increase gastric uptake and bioavailability of vitamins, minerals and phytonutrients. The proprietary fungal (plant-based) blend includes three key enzymes (proteases, lipases, and amylases), as well as Bioperine®, a derivative of black pepper.

Taurine (as Magnesium Taurate)

The sulphur-containing amino acid, Taurine (2-aminoethanesulfonic acid), is found in most tissues within the body. It is classified as a conditionally essential amino acid. In adults, it can be synthesized within the body and obtained from the diet, while infants acquire it from diet alone. Taurine is most concentrated in the heart and retina, with smaller concentrations found in the kidneys, intestine, skeletal muscle and brain, where it serves an a minor inhibitory neurotransmitter on its own.

Vitamin B6 (as pyridoxal-5’-phosphate)

Vitamin B6 is a water-soluble vitamin and part of the vitamin B complex group. Several forms of Vitamin B6 are known, but Pyridoxal-5’-Phosphate (P5P) is the active form. P5P is a cofactor for various reactions of amino acid metabolism.

5-Hydroxytryptophan (from Griffonia simplicifolia)

5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid, and metabolite of the protein building block L-tryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin. It is also commercially synthesized from the seeds of the African plant Griffonia simplicifolia.

The TNT™ formulas were developed by a multidisciplinary medical team who believes in providing patients with products that contain only active ingredients with proven safety and efficacy in humans, and supported by sufficient, credible scientific data.

EXCITATORY FORMULAS

Our excitatory support formulas are designed to increase the production of the catecholamines, DopamineNorepinephrine and Epinephrine, by providing essential precursors and cofactors for the catecholamine pathway.

Contegra™ | 60 tablets

Broad-spectrum support formula for the “wired and tired,” which supports inhibitory and excitatory neurotransmitter production*

Procite-D™ | 60 capsules

Naturally supports excitatory neurotransmission by rebuilding catecholamine pathways, particularly those for dopamine*

Featured Ingredients

Vitamin B6

Mucuna Pruriens

Magnesium

Siberian Ginseng

The TNT™ formulas were developed by a multidisciplinary medical team who believes in providing patients with products that contain only active ingredients with proven safety and efficacy in humans, and supported by sufficient, credible scientific data.

P5P

Coenzyme form of B6, cofactor for catecholamine pathway.

Methylfolate

Active form of folic acid, cofactor for catecholamine pathway; methyl donor.

Mucuna pruriens

Natural source of L-DOPA, direct precursor to Dopamine.

Siberian Ginseng (Eleutherococcus senticosus)

Adaptogenic herb to support adrenal function.

Trimethylglycine

Methylating agent; supports SAMe production, recycling; also a source of glycine, a minor inhibitory neurotransmitter.

N-Acetyl-L-Tyrosine

Precursor of catecholamine pathway.

DL-phenylalanine

“D” form to promote phenylethylamine (PEA) and thus increase Beta-endorphin production; also acts as an enkephalinase inhibitor; “L” form as a precursor to the catecholamine pathway.

SUPPORT FORMULAS

Along with the inhibitory and excitatory support formulas, the TNT™ formulas include those for additional support when creating natural protocols for your patients. These ingredient formulations focus on sleepsatietymethylation, and adrenal support.

Adaptacin™ | 60 tablets

Innovative formula combining adaptogens and adrenal cortex glandulars to tonify the adrenal gland and support adrenal function*

MethylMax™ | 60 tablets

SAMe, a primary methyl donor, has extensive scientific validation as an antidepressant, as well as for support of liver function and joint health.* SAMe is a critical cofactor for most major neurotransmitter biosynthetic pathways, including the conversion of Norepinephrine to Epinephrine

SomniTR™ | 30 tablets

Provides a low-dose support of melatonin production, and may help improve decreased GABA binding*

Plenus™ | 60/120 capsules

Suggested during neuroendocrine balancing when appetite and weight issues are indicated on the patient questionnaire

Featured Ingredients

Coleus forskohlii

Caralluma fimbriata

Garcinia Cambogia

Garcinia cambogia (Fruit)

Ashwagandha

Coleus forskohlii

A source of forskolin, known to increase cAMP, thereby promoting melatonin synthesis via contributing to the activation of serotonin N-acetyltransferase, the enzyme effecting conversion of serotonin into the intermediate N-acetylserotonin in the melatonin biosynthetic pathway.

Caralluma fimbriata

Standardized for 25% pregnene glycosides and 10% saponins, Caralluma is a succulent from India closely related to Hoodia gordonii. Studies demonstrate appetite suppression/satiety; proposed MOA is via the hypothalamus.

Garcinia cambogia (Fruit)

Also known as Brindall Berry, Garcinia is standardized for 50% hydroxycitric acids and 5% garcinol as a Ca salt; it has been demonstrated to control appetite and contribute to weight loss.

Ashwagandha (Withania somnifera)

Standardized for 5% withanolides; an adrenal adaptogen helping attenuate the effects of chronic stress.

Aphanizomenon flos-aquae

Certified organically grown by the State of Oregon, this blue-green algae is a dense source of nutrients and is standardized for 1% phenylethylamine content; shown to decrease hunger and promote satiety.

Trimethylglycine

Methylating agent; supports SAMe production, recycling; also a source of glycine, a minor inhibitory neurotransmitter.

NSB™

Sanesco International’s NSB™ is a proprietary nutrient absorption enhancement system containing compounds which are scientifically valid and evidence-based to increase gastric uptake and bioavailability of vitamins, minerals and phytonutrients. The proprietary fungal (plant) based blend includes three key enzymes (proteases, lipases, and amylases), as well as Bioperine®, a derivative of black pepper.

The TNT™ formulas were developed by a multidisciplinary medical team who believes in providing patients with products that contain only active ingredients with proven safety and efficacy in humans, and supported by sufficient, credible scientific data.
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