Tranquilent^TM

Balance between inhibitory and excitatory neurotransmitters is vital to health and well-being. Inhibitory neurotransmitters such as serotonin and GABA control excitatory signals in the nervous system. That’s why supporting inhibitory neurotransmitters often results in an overall calming and relaxing effect. 

Tranquilent includes ingredients that support the action of inhibitory neurotransmitters.* 5-HTP supports serotonin synthesis.* Myo-inositol works to support serotonergic receptors.*¹ Theanine, as Suntheanine®, supports both the release of GABA and its function.*^2,3

The chewable format makes Tranquilent easy to use for children and easy to take on the go as needed. It may also be combined with Lentra™, SomniTR™, or Prolent™ for added inhibitory support.* 

Tranquilent may be used in Initial, Restoration and Maintenance phases along the path to wellness.

L-theanine as Suntheanine® (standardized to >99%): Shown to promote relaxation by multiple mechanisms including antagonizing glutamate receptors, increasing the release of GABA and decreasing norepinephrine levels in the brain*^2,3

5-HTP: A naturally occurring amino acid and metabolite of L–tryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin.* Use of 5-HTP avoids the rate-limiting conversion of tryptophan to 5-HTP 

Myo-inositol (inositol) A precursor for the second messenger system (phosphatidyl-inositol) used by noradrenergic, cholinergic and serotonergic receptors.* Inositol regulates numerous cellular functions including membrane and receptor function*¹

Serving Size: 1 Chewable Tablet
Servings per Container: 30 Tablets

Tranquilent™ Formula  1,045mg  
Myo-inositol (inositol)
L-Theanine (as Suntheanine®)
5-hydroxytryptophan (Griffonia simplicifolia) (seed)

Suntheanine® brand L-Theanine is a registered trademark of Taiyo International, Inc.Suntheanine® is Generally Recognized as Safe (GRAS) and is Non-GMO Project Verified. 

GABA is important for: 

• Sleep⁴
• Calm and relaxation⁴
  
• Mood⁴
  
• Regulating excitability⁴
  

Serotonin also plays important roles in: 

• Mental and emotional health (including mood and anxiousness)⁵
  
• Aggression⁵
• Learning⁵
  
• Stress response⁵
  
• Appetite and cravings⁶
  
• Pain perception⁷
• Libido⁸ 
  
• GI motility⁹ 
  
• Thermoregulation¹⁰
• Menstrual health¹¹ 
  
• Sleep¹²  
• Calm and relaxation¹³  
• Muscle control and coordination¹⁴ 
  

Inositol is important for: 

• Mental and emotional health (including mood)¹
  
• Impulse control¹
  
• Fear response¹

1. Colodny L and Hoffman RL. Altern Med Rev. 1998;3(6):432-447. 
2. Eschenauer G and Sweet BV. Am J Healthy-Syst Pharm. 2006 Jan 1;63(1):26-30.  
3. Kakuda T, et al. Biosci Biotechnol Biochem. 2002;66(12):2683–2686.
4. Ngo D and Vo TS. Molecules. 2019;24(15):2678. 
5. Longone P, et al. Frontiers in endocrinology. (2011):2. 
6. Møller SE. (1992). Serotonin, carbohydrates, and atypical depression. Pharmacol Toxicol. 71 Suppl 1:61-71. Slide 19,20 
7. Wurtman J and Wurtman R. Curr Obes. Rep. 2018 Mar;7(1):1-5.
8. Ho KY, et al. Br J Anaesth. 2010 Setp;105(3):371-6.
9. Hull EM, et al. Physiology and Behavior. 2004 Nov;83(2):291-307.
10. Crowell MD. Br J Pharmacol. 2004 Apr;141(8):1285-93.
11. Rybaczy LA, et al. BMC Women’s Health. 2005. 
12. Yonkers KA, et al. ancet. 2008 Apr 5;371(9619):1200-1210.
13. Bravo R, et. al. Age (Dordr). 2013 Aug;35(4):1277-86.
14. Tauscher J, et al. The Amer J of Psychiatry. 2001 Aug 1;158(8):1326-1328.