Procite-D™ | 60 capsules
Procite-D™ is a catecholamine support formula specifically targeting Dopamine while also supporting Norepinephrine, Epinephrine, and Beta-endorphin pathways.

It supplies, in coenzymatic and/or phosphorylated/methylated form, B vitamins critical for proper neurotransmitter conversions.

*use only under direct supervision of a licensed healthcare provider

Procite-D™ is a catecholamine support formula specifically targeting Dopamine while also supporting Norepinephrine, Epinephrine, and Beta-endorphin pathways. It supplies, in coenzymatic and/or phosphorylated/methylated form, B vitamins critical for proper neurotransmitter conversions.
Mucuna Pruriens: Natural source of L-dopa, precursor to Dopamine.

DL-phenylalanine: Racemic source of “D” and “L” phenylalanine; “L” to support the catecholamine pathway and “D” to promote phenylethylamine (PEA) and thus promote Beta-endorphin production; also acts as an enkephalinase inhibitor, preventing endorphin breakdown.

N-acetyl-L-cysteine: Antioxidant; supports catecholamine pathway.

N-acetyl-L-tyrosine: Precursor of Dopamine, Norepinephrine, and Epinephrine; acetylated for bioavailability.

Vitamin B6 as Pyridoxal-5’-phosphate: Coenzyme form of Vitamin B6 as P5P; critical for neurotransmitter production.

Folic Acid: Cofactor in methylation reactions.

Methylcobalamin: Coenzyme form of Vitamin B12; methyl donor; important in neurotransmitter function.

Selenium: Trace element; detoxifier.

NSB™: Nutrient delivery system.

Procite-D™ supports excitatory neurotransmission through rebuilding catecholamine pathways, particularly dopamine.

Catecholamine deficiencies have been associated with fatigue, apathy, lack of focus, poor memory, decreased libido, and exhaustive depression. When optimized, catecholamines increase energy, focus, and a sense of well-being.

Use Procite-D™ in the rebalancing process to increase dopamine/catecholamines after inhibitory support has begun.

Special attention should be paid to ensuring optimal serotonin levels while using Procite-D™, because increasing catecholamine levels can suppress serotonin.

As a potent excitatory formula, Procite-D™ may be recommended in conjunction with Adaptacin™ or MethylMax™ for balancing the function of the catecholamine pathway and up-regulating the HPA-T axis.

Caution should be exercised when used in patients with a history of hypertension, bipolar, mania, or psychosis.

It is contraindicated in Phenylketonuria, or PKU.

Featured Ingredients

B12 Vitamin

Methylcobalamin is a coenzyme form of B12, which is the activated form necessary for nervous system health

Mucuna pruriens

Multiple studies have found that Mucuna pruriens contains a large amount of L-dopa, the precursor to dopamine, norepinephrine, and
epinphrine*

B9 | Folate

5-methyltetrahydrofolate, involved in the biosynthesis of nucleotides purines and pyrimidines and in the metabolism of several important amino acids

Bioperine®

Used to increase nutrient uptake in the gut*

The Natural Process

Tyrosine hydroxylase (TH) is found in all cells that synthesize catecholamines and is a mixed-function oxidase that uses molecular oxygen and tyrosine as its substrates and biopterin as its cofactor. TH is a homotetramer, each subunit of which has a molecular weight of approximately 60,000. It catalyzes the addition of a hydroxyl group to themeta position of tyrosine, thus forming 3,4-dihydroxy-l-phenylalanine (l-DOPA).

TH can also hydroxylate phenylalanine to form tyrosine, which is then converted to l-DOPA; this alternative synthetic route may be of significance in patients affected with phenylketonuria, a condition in which phenylalanine hydroxylase activity is depressed. TH has a Km for tyrosine in the micromolar range. As a result, it is virtually saturated by the high tissue concentrations of endogenous tyrosine.

The cofactor, biopterin, may be at Procite-D pathway-01subsaturating concentrations within catecholamine-containing neurons and, thus, may play an important role in regulating NE biosynthesis. TH is primarily a soluble enzyme; however, interactions with membrane constituents, such as phosphatidylserine, or with polyanions, such as heparin sulfate, have been shown to alter its kinetic characteristics. Analogs of tyrosine, such as α-methyl-p-tyrosine (AMPT), are competitive inhibitors of TH. Sequence analysis reveals consensus sequences for phosphorylation primarily in the N-terminal portion of the molecule. The gene reveals considerable sequence homology with phenylalanine hydroxylase and tryptophan hydroxylase. (source)

Patient Testimonial

Catherine | California

I have used Procite-D for 3 years; it was recommended by my MD when I felt tired and needed more focus for work in the afternoon. It works!

Patient Testimonial

Amanda | Oklahoma

Procite-D was recommended to me by my Internal Medicine specialist. I can tell a marked difference without it.