Contegra™ | 60 capsules
Contegra™ is a broad-spectrum support formula for the “wired and tired,” supporting inhibitory and excitatory neurotransmitter production, adrenal and thyroid function, and methylation pathways. It also supplies, in coenzymatic and/or phosphorylated form B vitamins critical for proper neurotransmitter function.

*use only under direct supervision of a licensed healthcare provider

Contegra™ is a broad-spectrum support formula for the “wired and tired,” supporting inhibitory and excitatory neurotransmitter production, adrenal and thyroid function, and methylation pathways. It also supplies, in coenzymatic and/or phosphorylated form B vitamins critical for proper neurotransmitter function.
Trimethylglycine: Methylating agent; also a source of glycine, an inhibitory amino acid neurotransmitter; TMG supports SAMe production/recycling.

L-theanine (as Suntheanine®): GABA-A receptor agonist; anxiolytic.*

N-acetyl-L-tyrosine: Precursor of Dopamine, Norepinephrine, and Epinephrine; acetylated for bioavailability.

Siberian Ginseng: Eleutherococcus senticosus, standardized for 0.8% eleutherosides; an adrenal adaptogen thought to attenuate the effects of chronic stress.

Pantethine: Biologically active form of Vitamin B5; adrenal support nutrient.

Vitamin B6 as Pyridoxal-5’-phosphate: Coenzyme form of Vitamin B6 as P5P; critical for neurotransmitter production.

Folic Acid: Cofactor in methylation reactions.

Methylcobalamin: Coenzyme form of Vitamin B12; methyl donor; important in neurotransmitter function.

Iodine: Essential component of T3 and T4 thyroid hormones.

NSB™: Nutrient delivery system.

Contegra™ is formulated for re-establishing HPA-T axis balance. Its ingredients allow for beginning excitatory support while continuing support for inhibitory function.

Contegra™ may be recommended when beginning excitatory support prior to more aggressive support due to continuing symptoms of anxiety, insomnia and stress.

Contegra™ is used to support patients with symptoms of fatigue, poor memory and focus, apathy, decreased libido and poor thyroid function. The addition of methylation support in Contegra™ helps prevent over-excitation as excitatory support is added to the patient’s protocol.

As balanced support for HPA-T axis function, it is often suggested after inhibitory support has begun (Prolent™, Lentra™, Tranquilent™) but prior to more potent excitatory support (Procite-D™) when patients indicate symptoms related to anxiety, agitated depression, or symptoms related to poor adrenal or thyroid function.

No specific contraindications known other than for individuals who are hypersensitive to any of the Contegra™ ingredients.

Featured Ingredients

L-theanine

Siberian Ginseng

Bioperine

B12 as methylcobalamin

The Natural Process

The interactions among these organs constitute the HPA axis, a major part of the neuroendocrine system that controls reactions to stress and regulates many body processes, Contegra pathway 2014-01including digestion, the immune system, mood and emotions, sexuality, and energy storage and expenditure.

It is the common mechanism for interactions among glands, hormones, and parts of the midbrain that mediate the general adaptation syndrome (GAS).[1]

While steroid hormones are produced mainly in vertebrates, the physiological role of the HPA axis and corticosteroids in stress response is so fundamental that analogous systems can be found in invertebrates and monocellular organisms as well. (source)