A bottle of SomniTR a neurotransmitter supplement
Targeted Nutritional support™


Delayed-Release Sleep Formula*

SomniTR™ is a delayed-release formula designed to initially release 1 mg of melatonin immediately after ingestion and 1 mg three hours later to help the patient stay asleep longer.*

SomniTR supports optimal melatonin production by supplementing multiple steps in the serotonin-to-melatonin pathway and also influences inhibitory GABAergic activity.*

encapsulating the Art & Science of Functional Nutrition™

Formula Overview

SomniTR™ 1

Reduced melatonin activity can contribute to prolonged sleep latency, inability to stay asleep, and overall disruption to healthy circadian rhythms, including occasional  jet lag.1 Circadian rhythm imbalances are hypothesized to contribute to increased appetite and weight gain.2

SomniTR provides melatonin and also provides support for healthy GABA-A receptor sites function.* Lactium have been shown to improve quality of optimal sleep by supporting GABA-A receptor activity.*3 ForsLean supports cAMP4 while pantothenic acid supports acetyl coenzyme A,5 both of which are important in healthy melatonin synthesis.*6

SomniTR provides support for healthy sleep and optimal circadian rhythm cycles. Consider in conjunction with Lentra, Prolent™ and/or Tranquilentto target additional pathway balances.

SomniTR contains ingredients that support melatonin production by supplementing multiple steps in the serotonin-to-melatonin pathway, and influencing balanced inhibitory GABAergic activity to impact multiple functional pathways connected to healthy sleep.

Lactium® Acts as a GABA-A receptor agonist, maintaining healthy receptor activity.*7 Lactium has been shown to decrease stress-related symptoms for balance in women and significantly improve healthy sleep quality.*3,7

ForsLean® (standardized to 20% forskolin) a source of forskolin that increases healthy cAMP activity.*4 Serotonin N-acetyltransferase requires cAMP to metabolize serotonin to N-acetylserotonin, the immediate precursor to melatonin.6

PantethinePrecursor to acetyl coenzyme A.*2 Production of N-acetylserotonin requires acetyl coenzyme A.6

Calcium (as Dicalcium Phosphate) potentiates the effects of cAMP.* Serotonin N-acetyltransferase requires cAMP to convert serotonin to the precursor to melatonin.5

Melatonin is a neurohormone involved with balanced circadian rhythm regulation and sleep induction.*2

Serving Size: 1 Tablet
Servings Per Container: 30 Tablets

SomniTR™ Formula  197mg  
Pantothenic Acid (as pantethine)
ForsLean® (Coleus forskohlii extract) (standardized for 20% forskolin) (root)

SomniTR™ 2
Lactium® is a registered trademark used under license and is
protected under U.S. patent #5,846,939.

SomniTR™ 3
ForsLean® is a registered trademark of Sabinsa Corporation and is the only Coleus forskohlii preparation supported commonly by Patent.

GABA balance is vital for: 

  • Optimal sleep9
  • Balanced calm and relaxation9
  • Healthy mood9
  • Regulating excitability9

Melatonin activity is critical for: 

  • Optimal sleep1,6
  1. Zisapel N. British Journal of Pharmacology. 2018;175: 3190-3199.
  2. Hardeland R, et al. Progress in Neurobiology. 2011; 93(3), 350-384.11. 
  3. de Saint-Hilaire ZD, et al. The Open Sleep Journal. 2009;3, 26-32.  
  4. Allen DO and Quesenberry JT. Journal of Pharmacology and Experimental Therapeutics.1988;244(3):852-858.
  5. Horvath Z and Vecsel L. Journal of Evidence-based Complementary & Alternative Medicine. 2011;16(1):21-28. 
  6. Klein DC, et al. Recent. Prog. Horm. 1997;52:307-357. 
  7. Miclo L, et al. The FASEB Journal express article. Published online 2001 Jun 8.
  8. Kim JH, et al. European Journal of Clinical Nutrition. 2007;61:536-541.
  9. Ngo D and Vo TS. Molecules. 2019;24(15):2678. 
SomniTR- a neurotransmitter supplement offering delayed release sleep support
delayed-release melatonin

Featured Ingredients

Lactium Logo


Bioactive Peptide

Acts as a GABA-A receptor agonist.*  Lactium has been shown to decrease stress-related symptoms in women and significantly improve sleep quality.*

Coleus forskohlii

Coleus Forskohlii

Herbal Ingredient

Forslean® (standardized to 20% forskolin) a source of forskolin that increases cAMP.*

Melatonin molecule

Delayed-Release Melatonin

Delayed-release melatonin is a neurohormone involved with circadian rhythm regulation and sleep induction.*

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Inhibitory Neurotransmitter


One of our feel-good neurotransmitters; Low levels of serotonin may relate to occasional symptoms like moodiness, sleep issues, and carb cravings.