Bottle of Tranquilent a neurotransmitter supplement
Targeted Nutritional support™


Chewable Inhibitory Support*

A unique, chewable, cherry and raspberry-flavored formula providing support for the inhibitory neurotransmitter system—both serotonergic and GABAergic neurotransmission.* May be used when calm or relaxation is needed in the short term as well as for rebalancing the inhibitory system over the long term.* Doses are appropriate for use in the pediatric population.  
Encapsulating The Art & Science of Functional NutritionTM

Formula Overview

Balance between inhibitory and excitatory neurotransmitter activity is vital to health and well-being. Inhibitory neurotransmitters such as serotonin and GABA maintain excitatory signals in the nervous system. That’s why supporting inhibitory neurotransmitters often results in a balanced calming and relaxing effect. 

Tranquilent includes ingredients that support the optimal function of inhibitory neurotransmitter activity.* 5-HTP is a precursor that supports serotonin synthesis.* Myo-inositol works to support healthy serotonergic receptors.*1 Theanine, as Suntheanine®, intake has been shown to increase GABA activity and function.*2

The chewable format makes Tranquilent easy to use for children and easy to take on the go as neededIt may also be combined with Lentra, SomniTR, or Prolent™ for added inhibitory support.* 

L-theanine as Suntheanine® (standardized to >99%): L-Theanine intake is shown to restore balanced relaxation by balancing multiple internal mechanisms, leading to increased healthy GABA activity while antagonizing glutamate receptors to support balance and decreased norepinephrine activity.*2,3

5-HTP:A naturally occurring amino acid and metabolite of Ltryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin.* Use of 5-HTP avoids the rate-limiting conversion of tryptophan to 5-HTP. 

Myo-inositol (inositol) A precursor for the second messenger system (phosphatidyl-inositol) used by noradrenergic, cholinergic and serotonergic receptors.* Inositol regulates numerous healthy cellular functions including optimal membrane and receptor function*1

Serving Size: 1 Chewable Tablet
Servings per Container: 30 Tablets

Tranquilent™ Formula  1,045mg  
Myo-inositol (inositol)
L-Theanine (as Suntheanine®)
5-hydroxytryptophan (Griffonia simplicifolia) (seed)


Tranquilent™ 1 Suntheanine® brand L-Theanine is a registered trademark of Taiyo International, Inc.Suntheanine® is Generally Recognized as Safe (GRAS) and is Non-GMO Project Verified. 

GABA and Serotonin are important for: 

  • Healthy sleep4,12
  • Balanced calm and relaxation4,13
  • Maintaining mood4
  • Regulating excitability4
  • Mental and emotional health balance (including mood and anxiousness)5
  • Optimal learning5
  • Balanced stress response5
  • Healthy appetite and craving support6
  • Occasional discomfort and pain7
  • Healthy libido8
  • Optimal GI motility9
  • Thermoregulation balance10
  • Menstrual health11 
  1. Colodny L and Hoffman RL. Altern Med Rev. 1998;3(6):432-447. 
  2. Nathan PJ, et al. 2006. J Herb Pharmacother. 6:21–30.
  3. Kimura and Morata. Chem Parhm Bull (Tokyo). 1986. Jul; 34 (7) 3053.7.
  4. Ngo D and Vo TS. Molecules. 2019;24(15):2678. 
  5. Longone P, et al. Frontiers in endocrinology. (2011):2. 
  6. Møller SE. (1992). Serotonin, carbohydrates, and atypical depression. Pharmacol Toxicol71 Suppl 1:61-71. Slide 19,20 
  7. Wurtman J and Wurtman R. Curr Obes. Rep. 2018 Mar;7(1):1-5.
  8. Ho KY, et al. Br J Anaesth. 2010 Setp;105(3):371-6.
  9. Hull EM, et al. Physiology and Behavior. 2004 Nov;83(2):291-307.
  10. Crowell MD. Br J Pharmacol. 2004 Apr;141(8):1285-93.
  11. Rybaczy LA, et al. BMC Women’s Health. 2005. 
  12. Yonkers KA, et al. ancet. 2008 Apr 5;371(9619):1200-1210.
  13. Bravo R, et. al. Age (Dordr). 2013 Aug;35(4):1277-86.
  14. Tauscher J, et al. The Amer J of Psychiatry. 2001 Aug 1;158(8):1326-1328.
Tranquilent- a neurotransmitter supplement for inhibitory support
gaba receptor support

Featured Ingredients


L-theanine (as Suntheanine®)

Amino Acid

Shown to promote relaxation by multiple mechanisms including antagonizing glutamate receptors, increasing the release of GABA and decreasing norepinephrine levels in the brain.*



Amino Acid

A naturally occurring amino acid and metabolite of L- tryptophan. 5-HTP is the direct precursor in the biosynthesis of serotonin.*

Inositol molecule

Myo-inositol (inositol)


A precursor for the second messenger system (phosphatidyl-inositol) used by noradrenergic, cholinergic and serotonergic receptors.* 


Tranquilent- a neurotransmitter supplement for inhibitory support

What They're Saying

I find it [Tranquilent] helpful for situations like behavioral issues, attention difficulties, anxiousness.* I find it especially helpful for kids.

Dennis Godby, ND

I hear stories in my office every day, but it’s not just about this product but the combination. With Sanesco’s products, people will say, “I can't believe how good I feel.”

Sharon Norling, MD, MBA

One of the features that parents like about it [Tranquilent] is that it seems to work very quickly.

Dennis Godby, ND
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Inhibitory Neurotransmitter


One of our feel-good neurotransmitters; Low levels of serotonin may relate to occasional symptoms like moodiness, sleep issues, and carb cravings. 

Learn why and how to test serotonin levels