A bottle of SomniTR a neurotransmitter supplement
Targeted Nutritional Therapy™


Delayed-Release Sleep Formula*

SomniTR™ is a delayed-release formula designed to initially release 1 mg of melatonin immediately after ingestion and 1 mg three hours later to help the patient stay asleep longer.*

SomniTR supports optimal melatonin production by supplementing multiple steps in the serotonin-to-melatonin pathway and also influences inhibitory GABAergic activity.*

encapsulating the Art & Science of Functional Nutrition™

Formula Overview

SomniTR™ 1

A deficiency in melatonin levels can contribute to prolonged sleep latency, inability to stay asleep, disruption to circadian rhythms and jet lag.1 Disordered circadian rhythm is hypothesized to contribute to increased appetite and weight gain.2 Melatonin also has the capability to reduce ACTH-stimulated cortisol production that has been found to interrupt sleep.2

The delayedrelease melatonin in SomniTR provides sustained levels for up to eight hours.

SomniTR also provides support for GABA-A receptor sites.* GABA-A agonists, such as Lactium have been shown to improve quality of sleep.*3 ForsLean supports cAMP4 while pantothenic acid supports acetyl coenzyme A,5 both of which are important in melatonin synthesis.*6

SomniTR provides support for patients with sleeping problems.* It may be taken in conjunction with Lentra, Prolent™ and/or Tranquilent.

SomniTR contains ingredients that support melatonin production by supplementing multiple steps in the serotonin-to-melatonin pathway or influence inhibitory GABAergic activity.* The tablet offers both immediate-release and delayed-release melaton into keep melatonin levels steady throughout the sleep cycle. 

Lactium® Acts as a GABA-A receptor agonist.*7 Lactium has been shown to decrease stress-related symptoms in women8 and significantly improve sleep quality.*3

ForsLean® (standardized to 20% forskolin) a source of forskolin that increases cAMP.*4 Serotonin N-acetyltransferase requires cAMP to metabolize serotonin to N-acetylserotonin, the immediate precursor to melatonin.6

PantethinePrecursor to acetyl coenzyme A.*2 Production of N-acetylserotonin requires acetyl coenzyme A.6

Calcium (as Dicalcium Phosphate) potentiates the effects of cAMP.* Serotonin N-acetyltransferase requires cAMP to convert serotonin to the precursor to melatonin.5

Melatonin is a neurohormone involved with circadian rhythm regulation and sleep induction.*2

Serving Size: 1 Tablet
Servings Per Container: 30 Tablets

SomniTR™ Formula  304mg  
Pantothenic Acid (as pantethine)
Calcium (as Dicalcium Phosphate)
ForsLean® (Coleus forskohlii extract) (standardized for 20% forskolin) (root)


SomniTR™ 2
Lactium® is a registered trademark used under license and is
protected under U.S. patent #5,846,939.

SomniTR™ 3
ForsLean® is a registered trademark of Sabinsa Corporation and is the only Coleus forskohlii preparation supported commonly by Patent.

GABA is vital for: 

  • Sleep9
  • Calm and relaxation9
  • Mood9
  • Regulating excitability9

Melatonin is critical for: 

  • Sleep1,6
  1. Zisapel N. British Journal of Pharmacology. 2018;175: 3190-3199.
  2. Hardeland R, et al. Progress in Neurobiology. 2011; 93(3), 350-384.11. 
  3. de Saint-Hilaire ZD, et al. The Open Sleep Journal. 2009;3, 26-32.  
  4. Allen DO and Quesenberry JT. Journal of Pharmacology and Experimental Therapeutics.1988;244(3):852-858.
  5. Horvath Z and Vecsel L. Journal of Evidence-based Complementary & Alternative Medicine. 2011;16(1):21-28. 
  6. Klein DC, et al. Recent. Prog. Horm. 1997;52:307-357. 
  7. Miclo L, et al. The FASEB Journal express article. Published online 2001 Jun 8.
  8. Kim JH, et al. European Journal of Clinical Nutrition. 2007;61:536-541.
  9. Ngo D and Vo TS. Molecules. 2019;24(15):2678. 
SomniTR- a neurotransmitter supplement offering delayed release sleep support
delayed-release melatonin

Featured Ingredients

Lactium Logo


Bioactive Peptide

Acts as a GABA-A receptor agonist.*  Lactium has been shown to decrease stress-related symptoms in women and significantly improve sleep quality.*

Coleus forskohlii

Coleus Forskohlii

Herbal Ingredient

Forslean® (standardized to 20% forskolin) a source of forskolin that increases cAMP.*

Melatonin molecule

Delayed-Release Melatonin

Delayed-release melatonin is a neurohormone involved with circadian rhythm regulation and sleep induction.*

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